Our Publications

NeuroWave is committed to protecting and maximizing the value of the technology it develops. We have assembled a large portfolio of intellectual property assets consisting of US and international patents, trademarks, and copyrights.

We are strongly committed to the dissemination of scientific information and routinely publish our research in peer reviewed journals and professional conferences.

small paper icon Publication List (pdf)

White Paper

  • S. Bibian and T. Zikov, “NeuroSENSE® Monitor with WAVCNS Cortical Quantifier: A Deterministic Approach to EEG Analysis,” NeuroWave Systems Inc., Cleveland Heights, OH, USA.

Journal and Conference Papers

  • G. Agrawal, M. Modarres, T. Zikov and S. Bibian, “NREM sleep staging using WAVCNS index,” Journal of Clinical Monitoring & Computing, vol. 25, no. 2, pp. 137-142, April 2011.
  • S. Bibian, G.A. Dumont and T. Zikov, “Dynamic Behavior of BIS, M-Entropy and NeuroSENSE Brain Function Monitors,” Journal of Clinical Monitoring & Computing, vol. 25, no. 1, pp. 81-87, February 2011.
  • S. Bibian, G.A. Dumont, M. Huzmezan and C.R. Ries, “Patient Variability and Uncertainty Quantification in Anesthesia: Part I - PKPD Modeling and Identification,” Proceedings of the 6th IFAC Symposium on Modeling and Control in Biomedical Systems , Reims, France, pp. 549-554, September 2006.
  • S. Bibian, G.A. Dumont, M. Huzmezan and C.R. Ries, “Patient Variability and Uncertainty Quantification in Anesthesia: Part II - PKPD Uncertainty,” Proceedings of the 6th IFAC Symposium on Modeling and Control in Biomedical Systems, Reims, France, pp. 555-560, September 2006.
  • T. Zikov, S. Bibian, G.A. Dumont, M. Huzmezan and C.R. Ries, “Quantifying Cortical Activity during General Anesthesia using Wavelet Analysis,” IEEE Transactions on Biomedical Engineering, vol. 53, no. 4, pp. 617-632, April 2006.
  • S. Bibian, C.R. Ries, M. Huzmezan and G.A. Dumont, “Introduction to Automated Drug Delivery in Clinical Anesthesia,” European Journal of Control, vol. 11, no. 6, pp. 535-557, June 2005.
  • S. Bibian, G.A. Dumont, M. Huzmezan and C.R. Ries, “Quantifying Uncertainty Bounds in Anesthetic PKPD Models,” Proceedings of the 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, San Francisco, CA, pp. 786-789, September 2004.
  • S. Bibian, C.R. Ries, M. Huzmezan and G.A. Dumont, “Clinical Anesthesia and Control Engineering: Terminology, Concepts and Issues,” Proceedings of the European Control Conference, Cambridge, UK, September 2003.
  • T. Zikov, S. Bibian, G.A. Dumont, M. Huzmezan and C.R. Ries, “A Wavelet Based De-noising Technique for Ocular Artifact Correction of the Electroencephalogram,” Proceedings of the Second Joint 24th Annual Conference of the Engineering in Medicine and Biology Society and Annual Fall Meeting of the Biomedical Engineering Society, pp. 98-105, October 2002.
  • S. Bibian, T. Zikov, G.A. Dumont, C.R. Ries, E. Puil, H. Ahmadi, M. Huzmezan and B.A. MacLeod, “Estimation of the Anesthetic Depth using Wavelet Analysis of Electroencephalogram,” Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 951-955, October 2001.

Clinical Abstracts

  • G. Agrawal, T. Zikov and S. Bibian, “Can NeuroSENSE Depth-of-Anesthesia Monitor be used for Sleep Monitoring in Hospitalized Patients?,” Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists, Chicago, IL, A504, October 2011.
  • G. Agrawal, T. Zikov and S. Bibian, “Robust and Real-Time Automatic Detection of Suppression in EEG Signals,” Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists, Chicago, IL, A503, October 2011.
  • G. Agrawal, S. Bibian and T. Zikov, “Recommended Clinical Range for WAVCNS Index during General Anesthesia,” Proceedings of the 2010 Annual Meeting of the American Society of Anesthesiologists, San Diego, CA, A1347, October 2010.
  • G. Agrawal, F. Clément, J.L. Scholtes, S. Bibian and T. Zikov, “Relationship between WAVCNS Index and Suppression Ratio,” Proceedings of the 2010 Annual Meeting of the American Society of Anesthesiologists, San Diego, CA, A1348, October 2010.
  • O. Pruszkowski, J. Bresson, N. Liu, T. Chazot and G. Agrawal, “Inter-Hemispheric Agreement of NeuroSENSE and BIS-XP Monitors during General Anesthesia,” Proceedings of the 2010 Annual Meeting of the American Society of Anesthesiologists, San Diego, CA, A1363, October 2010.
  • G. Agrawal, “Real-time Detection of Suppression in EEG,” Abstracts of the 21st Meeting of the European Society for Computing and Technology in Anesthesia and Intensive Care, Amsterdam, Netherlands, October 2010.
  • S. Bibian and T. Zikov, “Predictability of BIS, Entropy and NeuroSENSE,” Abstracts of the 20th Meeting of the European Society for Computing and Technology in Anesthesia and Intensive Care, Berlin, Germany, September 2009.
  • S. Bibian, F. Kaffashi, N. Chakravarthy, T. Zikov, M. Modarres, “NeuroMedicTM: An EEG-Based Field Deployable Seizure Detector,” Epilepsia, vol. 49(suppl. 7), pp. 381-382, 2008.
  • S. Bibian, T. Zikov, G.A. Dumont, C.R. Ries and M. Huzmezan, “Suitability of Consciousness Monitors for PD Modeling of Intravenous Anesthetic Drugs,” Abstracts of the 1st World Congress of Total Intravenous Anaesthesia - TCI, Venice, Italy, September 2007.
  • S. Bibian, G.A. Dumont, C.R. Ries and M. Huzmezan, “Suitability of Induction Data to Characterize the Static Drug vs. Response Relationship of Intravenous Drugs,” Abstracts of the 1st World Congress of Total Intravenous Anaesthesia - TCI, Venice, Italy, September 2007.
  • S. Bibian, G.A. Dumont, C.R. Ries and M. Huzmezan, “Process Control Identification Approach Applied to Propofol Pharmacodynamic Modeling,” Abstracts of the 1st World Congress of Total Intravenous Anaesthesia - TCI, Venice, Italy, September 2007.
  • S. Bibian, G.A. Dumont, C.R. Ries and M. Huzmezan, “Adequacy of the Traditional Pharmacodynamic Approach for Modeling Intravenous Anesthetics using EEG-Based Quantifiers of Cortical Activity,” Abstracts of the 1st World Congress of Total Intravenous Anaesthesia - TCI, Venice, Italy, September 2007.
  • S. Bibian, T. Zikov, D.M. Voltz, D.M. Voltz and A. Jaromczyk, “Influence of Incorrect Electrode Placement on Depth-of-Anesthesia Cortical Monitors,” Abstracts of the New York State Society of Anesthesiologists, 60th Annual Post Graduate Assembly, December 2006.
  • T. Zikov, D.M. Voltz, A.M. Jaromczyk and S. Bibian, “Potential of Cortical Depth-of-Anesthesia Monitors for Cerebral Injury Screening in Cardiac Surgery,” Anesthesiology, 105:A433, October 2006.
  • T. Zikov, S. Bibian, C.R. Ries, A.M. Jaromczyk and D.M. Voltz, “Performance of BIS and WAVCNS to Predict Loss of Consciousness during Routine Propofol Induction,” Anesthesiology, 105:A1030, October 2006.
  • S. Bibian, T. Zikov, C.R. Ries, D.M. Voltz and A.M. Jaromczyk, “Intra-Patient Reproducibility of the BIS and NeuroSENSE Monitors during Routine Propofol Induction,” Anesthesiology, 105:A1041, October 2006.
  • S. Bibian, C.R. Ries, G.A. Dumont, M. Huzmezan and T. Zikov, “Pharmacokinetic Delay during Propofol Induction and Monitor Dynamics: Effect on the Ke0 Calculation,” Anesthesiology, 105:A840, October 2006.
  • S. Bibian, C.R. Ries, G.A. Dumont, M. Huzmezan and T. Zikov, “Age Dependency of Propofol Median Effective Concentration (EC50),” Anesthesiology, 105:A842, October 2006.
  • D.M. Voltz, S. Bibian, M. Johns, C.R. Ries and A.M. Jaromczyk, “Potential Avoidance of Intra-Operative Awareness: A Case Report Using a Novel Consciousness Monitor,” Abstracts of the New York State Society of Anesthesiologists, 59th Annual Post Graduate Assembly, December 2005.
  • S. Bibian, T. Zikov, C.R. Ries, D.M. Voltz, G.A. Dumont and M. Huzmezan, “Intra- and Inter-Patient Variability of Processed Electroencephalography during Thiopental Induction for ECT,” Abstracts of the New York State Society of Anesthesiologists, 58th Annual Post Graduate Assembly, December 2004.
  • S. Bibian, T. Zikov, C.R. Ries, G.A. Dumont and M. Huzmezan, “The Wavelet-based Anesthetic Value (WAV): A Novel Alternative to the Bispectral Index (BIS),” Anesthesiology, 101:A342, October 2004.
  • K. K. Lundqvist, S. Bibian, C.R. Ries, P.Y.H. Yu and G.A. Dumont, “Can the Wavelet-based Anesthetic Value (WAV) Predict Airway Motor Response to LMA Insertion?,” Anesthesiology, 101:A606, October 2004.